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Targeting a previously undruggable target (SR-B1) in disease

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Zylem Biosciences is a biotechnology company developing targeted medicines based on its novel platform technology: A structural analog of natural high-density lipoprotein (HDL). Zylem has developed multiple formulations of therapies across multiple routes of administration, targeting diseases where lipid dysfunction plays a critical role. These include oncology and cardiovascular disease. Zylem’s team of innovative scientists, and experienced drug development management team is strategically built for success.

 
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The mission of Zylem Biosciences is to pioneer first-in-class therapies targeting SR-B1, a previously undruggable target.

 
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The core ZYL construct is a structural analog of natural high-density lipoprotein (HDL). The compound is highly targeted, has a potent sustained effect through its long half-life, and no off-target activity. It reduces cellular cholesterol, a pathogenic characteristic in oncology and cardiovascular disease, while simultaneously reducing inflammation and tuning the immune system. .